Catalog No. Size PriceQuantity
M24023-C Contact for quotation $100Unavailable


CMP8, a selective ligand for estrogen receptor, binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 exhibits IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, respectively.

Product information

CAS Number: 851107-28-3

Molecular Weight: 528.08

Formula: C33H34ClNO3

Chemical Name: 9a-[(4-chlorophenyl)methyl]-7-hydroxy-4-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2,3,9,9a-tetrahydro-1H-fluoren-3-one

Smiles: OC1=CC2CC3(CC4C=CC(Cl)=CC=4)CCC(=O)C(=C3C=2C=C1)C1C=CC(=CC=1)OCCN1CCCCC1


InChi: InChI=1S/C33H34ClNO3/c34-26-8-4-23(5-9-26)21-33-15-14-30(37)31(32(33)29-13-10-27(36)20-25(29)22-33)24-6-11-28(12-7-24)38-19-18-35-16-2-1-3-17-35/h4-13,20,36H,1-3,14-19,21-22H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

CMP8 (Compound 20h) is dosed in male Balb-c mice (4 mg/kg, ip). The plasma concentration after 4 h is 1.5-fold its EC50 in mammalian cells with a Cmax of 0.5 µM after 30 min.

Products are for research use only. Not for human use.

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