6-O-Methacrylate


Catalog No. Size PriceQuantity
M24059-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity.

Product information

CAS Number: 950685-51-5

Molecular Weight: 450.48

Formula: C23H30O9

Chemical Name: (3aR,4R,4aS,5R,8R,8aR,9S,9aR)-8,9-bis(acetyloxy)-5-hydroxy-5,8a-dimethyl-3-methylidene-2-oxo-dodecahydronaphtho[2,3-b]furan-4-yl 2-methylprop-2-enoate

Smiles: CC(=C)C(=O)O[C@@H]1[C@@H]2[C@@H](OC(=O)C2=C)[C@@H](OC(C)=O)[C@@]2(C)[C@@H](CC[C@@](C)(O)[C@@H]21)OC(C)=O

InChiKey: GDIVEWNXVQCYQL-ZVSMCMQZSA-N

InChi: InChI=1S/C23H30O9/c1-10(2)20(26)31-16-15-11(3)21(27)32-17(15)19(30-13(5)25)23(7)14(29-12(4)24)8-9-22(6,28)18(16)23/h14-19,28H,1,3,8-9H2,2,4-7H3/t14-,15-,16-,17-,18+,19-,22-,23+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

6-O-Methacrylate (10 μg/mL) shows anti-TMV activities in the pretreated tobacco plants with inhibition rate of 59.6%.

Products are for research use only. Not for human use.

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