Description
Ac-Arg-Gly-Lys(Ac)-AMC is a substrate for HDAC.
Product information
CAS Number: 660846-97-9
Molecular Weight: 600.67
Formula: C28H40N8O7
Chemical Name: (2S)-2-{2-[(2S)-5-[(diaminomethylidene)amino]-2-acetamidopentanamido]acetamido}-6-acetamido-N-(4-methyl-2-oxo-2H-chromen-7-yl)hexanamide
Smiles: CC1=CC(=O)OC2=CC(=CC=C12)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(C)=O
InChiKey: HABKINWCDDLXSZ-VXKWHMMOSA-N
InChi: InChI=1S/C28H40N8O7/c1-16-13-25(40)43-23-14-19(9-10-20(16)23)35-27(42)22(7-4-5-11-31-17(2)37)36-24(39)15-33-26(41)21(34-18(3)38)8-6-12-32-28(29)30/h9-10,13-14,21-22H,4-8,11-12,15H2,1-3H3,(H,31,37)(H,33,41)(H,34,38)(H,35,42)(H,36,39)(H4,29,30,32)/t21-,22-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Following initial inhibition of HDACs, the peptide substrate Ac-Arg-Gly-Lys-AMC is added to the reaction tubes for next 30 min and finally the stop solution stopped the reaction mediated by HDAC enzymes.
Products are for research use only. Not for human use.
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