Description
IQB-782 is a cysteine derivative. IQB-782 has inhibition for thrombin activatable fibrinolysis inhibitor (TAFI), with an Ki(app) of 0.14 μM. IQB-782 shows a potent mucolytic-expectorant activity.
Product information
CAS Number: 40454-21-5
Molecular Weight: 163.20
Formula: C4H9N3O2S
Chemical Name: (2R)-2-[(diaminomethylidene)amino]-3-sulfanylpropanoic acid
Smiles: NC(N)=N[C@@H](CS)C(O)=O
InChiKey: XWRZKLKALVJDDS-REOHCLBHSA-N
InChi: InChI=1S/C4H9N3O2S/c5-4(6)7-2(1-10)3(8)9/h2,10H,1H2,(H,8,9)(H4,5,6,7)/t2-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
IQB-782 inhibits TAFI related carboxypeptidases with IC50s of 49 μM and 12 μM for CPN and CPB, respectively.
Products are for research use only. Not for human use.
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