BC-1258


Catalog No. Size PriceQuantity
M24299-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

BC-1258, an F-box/LRR-repeat protein 2 (FBXL2) activator, can stabilize and upregulate FBXL2 levels. BC-1258 induces apoptosis of tumorigenic cells, and profoundly inhibits tumor formation in mice.

Product information

CAS Number: 1507370-40-2

Molecular Weight: 406.57

Formula: C22H22N4S2

Chemical Name: {[4-(1,3-thiazol-2-yl)phenyl]methyl}[2-({[4-(1,3-thiazol-2-yl)phenyl]methyl}amino)ethyl]amine

Smiles: C(NCCNCC1C=CC(=CC=1)C1=NC=CS1)C1C=CC(=CC=1)C1=NC=CS1

InChiKey: FRTSLZJCGAFSET-UHFFFAOYSA-N

InChi: InChI=1S/C22H22N4S2/c1-5-19(21-25-11-13-27-21)6-2-17(1)15-23-9-10-24-16-18-3-7-20(8-4-18)22-26-12-14-28-22/h1-8,11-14,23-24H,9-10,15-16H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

BC-1258 是一种 F-box/LRR-重复蛋白 2 (FBXL2) 激活剂,可以稳定和上调 FBXL2 水平。BC-1258 诱导致瘤细胞凋亡,并显着抑制小鼠的肿瘤形成。

In Vivo:

BC-1258 (30 μg/mL in the drinking water) significantly reduces tumor size and weight in athymic nude mice.

Products are for research use only. Not for human use.

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