Description
Propargyl-C8-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 1006592-59-1
Molecular Weight: 438.51
Formula: C22H34N2O7
Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-{2-[2-(undec-10-ynamido)ethoxy]ethoxy}propanoate
Smiles: C#CCCCCCCCCC(=O)NCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChiKey: OMCLMLMPUVUIQP-UHFFFAOYSA-N
InChi: InChI=1S/C22H34N2O7/c1-2-3-4-5-6-7-8-9-10-19(25)23-14-16-30-18-17-29-15-13-22(28)31-24-20(26)11-12-21(24)27/h1H,3-18H2,(H,23,25)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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