N-Benzyl-N-bis(PEG3-acid)


Catalog No. Size PriceQuantity
M24600-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

N-Benzyl-N-bis(PEG3-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2093154-03-9

Molecular Weight: 515.59

Formula: C25H41NO10

Chemical Name: 13-benzyl-4,7,10,16,19,22-hexaoxa-13-azapentacosanedioic acid

Smiles: OC(=O)CCOCCOCCOCCN(CC1C=CC=CC=1)CCOCCOCCOCCC(O)=O

InChiKey: YQSOIFQMGAZDSN-UHFFFAOYSA-N

InChi: InChI=1S/C25H41NO10/c27-24(28)6-10-31-14-18-35-20-16-33-12-8-26(22-23-4-2-1-3-5-23)9-13-34-17-21-36-19-15-32-11-7-25(29)30/h1-5H,6-22H2,(H,27,28)(H,29,30)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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