Description
Azido-PEG4-nitrile is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2194563-82-9
Molecular Weight: 272.30
Formula: C11H20N4O4
Chemical Name: 1-azido-3,6,9,12-tetraoxapentadecane-15-nitrile
Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCC#N
InChiKey: GCUNQSAEBVDFRE-UHFFFAOYSA-N
InChi: InChI=1S/C11H20N4O4/c12-2-1-4-16-6-8-18-10-11-19-9-7-17-5-3-14-15-13/h1,3-11H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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