4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene


Catalog No. Size PriceQuantity
M24833-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 160854-54-6

Molecular Weight: 374.43

Formula: C17H14N2O4S2

Chemical Name: 2,5-dioxopyrrolidin-1-yl 4-[(pyridin-2-yldisulfanyl)methyl]benzoate

Smiles: O=C(ON1C(=O)CCC1=O)C1=CC=C(CSSC2=CC=CC=N2)C=C1

InChiKey: VNWUUFREFCAFEV-UHFFFAOYSA-N

InChi: InChI=1S/C17H14N2O4S2/c20-15-8-9-16(21)19(15)23-17(22)13-6-4-12(5-7-13)11-24-25-14-3-1-2-10-18-14/h1-7,10H,8-9,11H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Products are for research use only. Not for human use.

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