Description
AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes.
Product information
CAS Number: 613260-13-2
Molecular Weight: 438.69
Formula: C16H8ClF5N2O5
Chemical Name: 4-({[(2-chloro-4,5-difluorophenyl)formamido]carbonyl}amino)-3-(trifluoromethoxy)benzoic acid
Smiles: OC(=O)C1=CC(OC(F)(F)F)=C(C=C1)NC(=O)NC(=O)C1=CC(F)=C(F)C=C1Cl
InChiKey: NWQGDIBCFLDHDO-UHFFFAOYSA-N
InChi: InChI=1S/C16H8ClF5N2O5/c17-8-5-10(19)9(18)4-7(8)13(25)24-15(28)23-11-2-1-6(14(26)27)3-12(11)29-16(20,21)22/h1-5H,(H,26,27)(H2,23,24,25,28)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively).
Products are for research use only. Not for human use.
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