Povidone iodine


Catalog No. Size PriceQuantity
M25019-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Povidone iodine (iodopovidone) displays excellent antibacterial activity which can against MRSA and MSSA strains with MICs of 31.25 mg/L and 7.82 mg/L, respectively.

Product information

CAS Number: 25655-41-8

Molecular Weight: 364.95

Formula: C6H9I2NO

Chemical Name: 1-ethenylpyrrolidin-2-one; diiodine

Smiles: C=CN1CCCC1=O.II

InChiKey: CPKVUHPKYQGHMW-UHFFFAOYSA-N

InChi: InChI=1S/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 15 mg/mL (Need ultrasonic). H2O : 2.4 mg/mL (Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

MIC values of Povidone iodine (iodopovidone) (PVP-I) are 31.25 mg/L and 7.82 mg/L, respectively. Treatment of the cells with Povidone iodine (PVP-I) at a dilution of 1:32 causes a sharp reduction in cell viability by 90-95% on all testing cell lines.

In Vivo:

The Dp+Povidone iodine (iodopovidone) (PVP-I) group has the second highest average score from day 13 to the end of the experimental period. The Dp+Povidone iodine and Dp+Et-OH groups also show a significantly increase in eosinophil count compare with the control group (p<0.05 and p<0.001, respectively). However, the eosinophil count does not significantly differ among the Dp+Povidone iodine (PVP-I), Dp+CHG, and Dp+vehicle groups.

Products are for research use only. Not for human use.

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