Description
1, 7-Bis-Boc-1, 4, 7-triazaheptane, CAS No. 117499-16-8, is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 117499-16-8
Molecular Weight: 303.40
Formula: C14H29N3O4
Chemical Name: tert-butyl N-{2-[(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]ethyl}carbamate
Smiles: CC(C)(C)OC(=O)NCCNCCNC(=O)OC(C)(C)C
InChiKey: KNORWRWRHNHJAV-UHFFFAOYSA-N
InChi: InChI=1S/C14H29N3O4/c1-13(2,3)20-11(18)16-9-7-15-8-10-17-12(19)21-14(4,5)6/h15H,7-10H2,1-6H3,(H,16,18)(H,17,19)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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