Description
Azido-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2170240-96-5
Molecular Weight: 305.33
Formula: C11H23N5O5
Chemical Name: 1-azido-3,6,9,12-tetraoxapentadecane-15-hydrazide
Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCC(=O)NN
InChiKey: BUAWGAVOHIVJRC-UHFFFAOYSA-N
InChi: InChI=1S/C11H23N5O5/c12-15-11(17)1-3-18-5-7-20-9-10-21-8-6-19-4-2-14-16-13/h1-10,12H2,(H,15,17)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (327.51 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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