Description
Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1091627-77-8
Molecular Weight: 424.53
Formula: C19H40N2O8
Chemical Name: tert-butyl N-(20-amino-3,6,9,12,15,18-hexaoxaicosan-1-yl)carbamate
Smiles: CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCN
InChiKey: HYSRAUNKYCBBFY-UHFFFAOYSA-N
InChi: InChI=1S/C19H40N2O8/c1-19(2,3)29-18(22)21-5-7-24-9-11-26-13-15-28-17-16-27-14-12-25-10-8-23-6-4-20/h4-17,20H2,1-3H3,(H,21,22)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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