Cbz-NH-PEG8-C2-acid


Catalog No. Size PriceQuantity
M25119-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Cbz-NH-PEG8-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1334177-87-5

Molecular Weight: 575.65

Formula: C27H45NO12

Chemical Name: 1-{[(benzyloxy)carbonyl]amino}-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid

Smiles: OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1C=CC=CC=1

InChiKey: ISVOBOLHCFBPFZ-UHFFFAOYSA-N

InChi: InChI=1S/C27H45NO12/c29-26(30)6-8-32-10-12-34-14-16-36-18-20-38-22-23-39-21-19-37-17-15-35-13-11-33-9-7-28-27(31)40-24-25-4-2-1-3-5-25/h1-5H,6-24H2,(H,28,31)(H,29,30)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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