Azido-PEG5-CH2CO2-PFP


Catalog No. Size PriceQuantity
M25233-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 2144777-92-2

Molecular Weight: 487.38

Formula: C18H22F5N3O7

Chemical Name: 2,3,4,5,6-pentafluorophenyl 17-azido-3,6,9,12,15-pentaoxaheptadecanoate

Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCC(=O)OC1C(F)=C(F)C(F)=C(F)C=1F

InChiKey: NITGTHWASXRERB-UHFFFAOYSA-N

InChi: InChI=1S/C18H22F5N3O7/c19-13-14(20)16(22)18(17(23)15(13)21)33-12(27)11-32-10-9-31-8-7-30-6-5-29-4-3-28-2-1-25-26-24/h1-11H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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