Biotin-EDA


Catalog No. Size PriceQuantity
M25250-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 111790-37-5

Molecular Weight: 286.39

Formula: C12H22N4O2S

Chemical Name: 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(2-aminoethyl)pentanamide

Smiles: NCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

InChiKey: BNCJEZWKLUBUBB-QXEWZRGKSA-N

InChi: InChI=1S/C12H22N4O2S/c13-5-6-14-10(17)4-2-1-3-9-11-8(7-19-9)15-12(18)16-11/h8-9,11H,1-7,13H2,(H,14,17)(H2,15,16,18)/t8-,9-,11-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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