ANB-NOS


Catalog No. Size PriceQuantity
M25298-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

ANB-NOS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 60117-35-3

Molecular Weight: 305.20

Formula: C11H7N5O6

Chemical Name: 2,5-dioxopyrrolidin-1-yl 5-azido-2-nitrobenzoate

Smiles: [N-]=[N+]=NC1=CC(=C(C=C1)[N+]([O-])=O)C(=O)ON1C(=O)CCC1=O

InChiKey: FUOJEDZPVVDXHI-UHFFFAOYSA-N

InChi: InChI=1S/C11H7N5O6/c12-14-13-6-1-2-8(16(20)21)7(5-6)11(19)22-15-9(17)3-4-10(15)18/h1-2,5H,3-4H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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