Fluorescein-PEG6-NHS ester


Catalog No. Size PriceQuantity
M25376-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Fluorescein-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1818294-35-7

Molecular Weight: 839.86

Formula: C40H45N3O15S

Chemical Name: 2,5-dioxopyrrolidin-1-yl 1-[({3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-5-yl}carbamothioyl)amino]-3,6,9,12,15,18-hexaoxahenicosan-21-oate

Smiles: OC1=CC2OC3=CC(O)=CC=C3C3(OC(=O)C4=CC(=CC=C34)NC(=S)NCCOCCOCCOCCOCCOCCOCCC(=O)ON3C(=O)CCC3=O)C=2C=C1

InChiKey: JRSZEPYWIPLVEA-UHFFFAOYSA-N

InChi: InChI=1S/C40H45N3O15S/c44-27-2-5-31-33(24-27)56-34-25-28(45)3-6-32(34)40(31)30-4-1-26(23-29(30)38(49)57-40)42-39(59)41-10-12-51-14-16-53-18-20-55-22-21-54-19-17-52-15-13-50-11-9-37(48)58-43-35(46)7-8-36(43)47/h1-6,23-25,44-45H,7-22H2,(H2,41,42,59)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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