Bis-PEG4-t-butyl ester


Catalog No. Size PriceQuantity
M25394-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Bis-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2100306-53-2

Molecular Weight: 406.51

Formula: C20H38O8

Chemical Name: 1,16-di-tert-butyl 4,7,10,13-tetraoxahexadecanedioate

Smiles: CC(C)(C)OC(=O)CCOCCOCCOCCOCCC(=O)OC(C)(C)C

InChiKey: BEMRKFMWPQHBBR-UHFFFAOYSA-N

InChi: InChI=1S/C20H38O8/c1-19(2,3)27-17(21)7-9-23-11-13-25-15-16-26-14-12-24-10-8-18(22)28-20(4,5)6/h7-16H2,1-6H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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