SPDP-PEG4-acid


Catalog No. Size PriceQuantity
M25417-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

SPDP-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 581065-97-6

Molecular Weight: 462.58

Formula: C19H30N2O7S2

Chemical Name: 1-[3-(pyridin-2-yldisulfanyl)propanamido]-3,6,9,12-tetraoxapentadecan-15-oic acid

Smiles: OC(=O)CCOCCOCCOCCOCCNC(=O)CCSSC1=CC=CC=N1

InChiKey: IJDPYTZOKIVWAN-UHFFFAOYSA-N

InChi: InChI=1S/C19H30N2O7S2/c22-17(5-16-29-30-18-3-1-2-6-21-18)20-7-9-26-11-13-28-15-14-27-12-10-25-8-4-19(23)24/h1-3,6H,4-5,7-16H2,(H,20,22)(H,23,24)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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