Azido-PEG5-succinimidyl carbonate


Catalog No. Size PriceQuantity
M25447-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Azido-PEG5-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1402411-88-4

Molecular Weight: 448.43

Formula: C17H28N4O10

Chemical Name: 1-[(19-azido-2,5,8,11,14,17-hexaoxanonadecanoyl)oxy]pyrrolidine-2,5-dione

Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCOC(=O)ON1C(=O)CCC1=O

InChiKey: RDPYDXXYIRLZAG-UHFFFAOYSA-N

InChi: InChI=1S/C17H28N4O10/c18-20-19-3-4-25-5-6-26-7-8-27-9-10-28-11-12-29-13-14-30-17(24)31-21-15(22)1-2-16(21)23/h1-14H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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