Description
Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 653600-56-7
Molecular Weight: 430.37
Formula: C16H22N4O10
Chemical Name: [(2R,3R,4R,5R)-3,4,6-tris(acetyloxy)-5-(2-azidoacetamido)oxan-2-yl]methyl acetate
Smiles: CC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@H](NC(=O)CN=[N+]=[N-])C(O[C@@H]1COC(C)=O)OC(C)=O
InChiKey: HGMISDAXLUIXKM-YJUJGKJLSA-N
InChi: InChI=1S/C16H22N4O10/c1-7(21)26-6-11-14(27-8(2)22)15(28-9(3)23)13(16(30-11)29-10(4)24)19-12(25)5-18-20-17/h11,13-16H,5-6H2,1-4H3,(H,19,25)/t11-,13-,14+,15-,16?/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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