SDZ285428


Catalog No. Size PriceQuantity
M25604-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

SDZ285428 is a CYP51 inhibitor. SDZ285428 inhibits Trypanosoma cruzi (TC) CYP51 with I/E2 <1 (5 min) and I/E2=9 (1 h). SDZ285428 inhibits Trypanosoma brucei (TB) CYP51 with I/E2 <1 (5 min) and I/E2=35 (1 h).

Product information

CAS Number: 174262-13-6

Molecular Weight: 401.89

Formula: C24H20ClN3O

Chemical Name: 4'-chloro-N-[2-(1H-imidazol-1-yl)-2-phenylethyl]-[1,1'-biphenyl]-4-carboxamide

Smiles: O=C(NCC(C1C=CC=CC=1)N1C=NC=C1)C1C=CC(=CC=1)C1C=CC(Cl)=CC=1

InChiKey: FHHNSSGZEIVGMS-UHFFFAOYSA-N

InChi: InChI=1S/C24H20ClN3O/c25-22-12-10-19(11-13-22)18-6-8-21(9-7-18)24(29)27-16-23(28-15-14-26-17-28)20-4-2-1-3-5-20/h1-15,17,23H,16H2,(H,27,29)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (124.41 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Specific inhibition of protozoan CYP51 can potentially provide treatment for human trypanosomiases.

Products are for research use only. Not for human use.

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