Icariside D2


Catalog No. Size PriceQuantity
M25620-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 μM. Icariside D2 induces apoptosis .

Product information

CAS Number: 38954-02-8

Molecular Weight: 300.30

Formula: C14H20O7

Chemical Name: (2S,3R,4S,5S,6R)-2-[4-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Smiles: O[C@@H]1[C@@H](CO)O[C@@H](OC2C=CC(CCO)=CC=2)[C@H](O)[C@H]1O

InChiKey: OJDSCNUKKOKOQJ-RKQHYHRCSA-N

InChi: InChI=1S/C14H20O7/c15-6-5-8-1-3-9(4-2-8)20-14-13(19)12(18)11(17)10(7-16)21-14/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Icariside D2 3 induces apoptosis via alteration of expression of apoptosis-related proteins and decreases phosphorylation of AKT in HL-60 cells. Icariside D2 exhibits anti-inflammatory and anti-HIV activity.

Products are for research use only. Not for human use.

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