Description
Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 μM. Icariside D2 induces apoptosis .
Product information
CAS Number: 38954-02-8
Molecular Weight: 300.30
Formula: C14H20O7
Chemical Name: (2S,3R,4S,5S,6R)-2-[4-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
Smiles: O[C@@H]1[C@@H](CO)O[C@@H](OC2C=CC(CCO)=CC=2)[C@H](O)[C@H]1O
InChiKey: OJDSCNUKKOKOQJ-RKQHYHRCSA-N
InChi: InChI=1S/C14H20O7/c15-6-5-8-1-3-9(4-2-8)20-14-13(19)12(18)11(17)10(7-16)21-14/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Icariside D2 3 induces apoptosis via alteration of expression of apoptosis-related proteins and decreases phosphorylation of AKT in HL-60 cells. Icariside D2 exhibits anti-inflammatory and anti-HIV activity.
Products are for research use only. Not for human use.
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