Description
4-Methylumbelliferyl phosphate (4-MUP) is a fluorogenic substrate of alkaline phosphatases.
Product information
CAS Number: 3368-04-5
Molecular Weight: 256.15
Formula: C10H9O6P
Chemical Name: [(4-methyl-2-oxo-2H-chromen-7-yl)oxy]phosphonic acid
Smiles: CC1=CC(=O)OC2=CC(=CC=C21)OP(O)(O)=O
InChiKey: BCHIXGBGRHLSBE-UHFFFAOYSA-N
InChi: InChI=1S/C10H9O6P/c1-6-4-10(11)15-9-5-7(2-3-8(6)9)16-17(12,13)14/h2-5H,1H3,(H2,12,13,14)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : 20.83 mg/mL (81.32 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
4-Methylumbelliferyl phosphate monoester previously described as one of a series of 4-methylumbelliferone conjugates is later found to be the PlP2-pyrophosphate diester and is not hydrolysed by serum phosphomonoesterases . 4-Methylumbelliferyl phosphate has a significant advantage over currently available substrates in that its useful concentration range extends to about 0.1 μM. If the concentration of 4-Methylumbelliferyl phosphate is held constant and the pH is varied, the activity of the enzyme passes through a maximum.
Products are for research use only. Not for human use.
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