Description
hDDAH-1-IN-1 TFA (compound 8a) is a potent and selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), with a Ki of 18 µM.
Product information
CAS Number: 1229238-70-3
Molecular Weight: 416.32
Formula: C12H22F6N4O5
Chemical Name: N''-(4-aminobutyl)-N-(2-methoxyethyl)guanidine; bis(trifluoroacetic acid)
Smiles: COCCNC(N)=NCCCCN.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F
InChiKey: XIZCXZOQUJTQLD-UHFFFAOYSA-N
InChi: InChI=1S/C8H20N4O.2C2HF3O2/c1-13-7-6-12-8(10)11-5-3-2-4-9;2*3-2(4,5)1(6)7/h2-7,9H2,1H3,(H3,10,11,12);2*(H,6,7)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
hDDAH-1-IN-1 TFA potently inhibits hDDAH-1 (Ki = 18 µM) without significantly affecting NOSs and arginase.
Products are for research use only. Not for human use.
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