Siremadlin (R Enantiomer)


Catalog No. Size PriceQuantity
M25841-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Siremadlin R Enantiomer (NVP-HDM201 R Enantiomer) is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific MDM-2/p53 inhibitor.

Product information

CAS Number: 1448867-42-2

Molecular Weight: 555.41

Formula: C26H24Cl2N6O4

Chemical Name: 5-chloro-3-[(6R)-6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-4-oxo-1-(propan-2-yl)-1H,4H,5H,6H-pyrrolo[3,4-d]imidazol-5-yl]-1-methyl-1,2-dihydropyridin-2-one

Smiles: CN1C=C(Cl)C=C(C1=O)N1[C@@H](C2=C(N=C(C3=CN=C(N=C3OC)OC)N2C(C)C)C1=O)C1=CC=C(Cl)C=C1

InChiKey: AGBSXNCBIWWLHD-HXUWFJFHSA-N

InChi: InChI=1S/C26H24Cl2N6O4/c1-13(2)33-21-19(30-22(33)17-11-29-26(38-5)31-23(17)37-4)25(36)34(18-10-16(28)12-32(3)24(18)35)20(21)14-6-8-15(27)9-7-14/h6-13,20H,1-5H3/t20-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 56.75 mg/mL (102.18 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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