Gefitinib impurity 1


Catalog No. Size PriceQuantity
M25913-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Gefitinib impurity 1 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity.

Product information

CAS Number: 675126-26-8

Molecular Weight: 321.33

Formula: C15H19N3O5

Chemical Name: 4-methoxy-5-[3-(morpholin-4-yl)propoxy]-2-nitrobenzonitrile

Smiles: COC1=CC(=C(C=C1OCCCN1CCOCC1)C#N)[N+]([O-])=O

InChiKey: FYCDMKYKGPHRFW-UHFFFAOYSA-N

InChi: InChI=1S/C15H19N3O5/c1-21-14-10-13(18(19)20)12(11-16)9-15(14)23-6-2-3-17-4-7-22-8-5-17/h9-10H,2-8H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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