HMG499


Catalog No. Size PriceQuantity
M25946-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC50 of 0.41 μM. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serum cholesterol levels and decrease atherosclerosis.

Product information

CAS Number: 2416941-68-7

Molecular Weight: 498.78

Formula: C33H54O3

Chemical Name: (1R,4R,7S,9aR,11aR)-1-[(2R)-6-hydroxy-6-(prop-2-en-1-yl)non-8-en-2-yl]-6,6,9a,11a-tetramethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-4,7-diol

Smiles: CC1(C)[C@@H](O)CC[C@]2(C)C3CC[C@@]4(C)C(CC[C@@H]4[C@H](C)CCCC(O)(CC=C)CC=C)C3[C@@H](O)C=C12

InChiKey: LPLLZSOEZAVGBO-FUICJWFRSA-N

InChi: InChI=1S/C33H54O3/c1-8-16-33(36,17-9-2)18-10-11-22(3)23-12-13-24-29-25(14-19-31(23,24)6)32(7)20-15-28(35)30(4,5)27(32)21-26(29)34/h8-9,21-26,28-29,34-36H,1-2,10-20H2,3-7H3/t22-,23-,24?,25?,26+,28+,29?,31-,32-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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