1, 3, 5, 8-Tetrahydroxyxanthone


Catalog No. Size PriceQuantity
M25992-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity.

Product information

CAS Number: 2980-32-7

Molecular Weight: 260.20

Formula: C13H8O6

Chemical Name: 1,3,5,8-tetrahydroxy-9H-xanthen-9-one

Smiles: OC1C=C(O)C2C(=O)C3=C(OC=2C=1)C(O)=CC=C3O

InChiKey: MPXAWSABMVLIBU-UHFFFAOYSA-N

InChi: InChI=1S/C13H8O6/c14-5-3-8(17)10-9(4-5)19-13-7(16)2-1-6(15)11(13)12(10)18/h1-4,14-17H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) attenuates lipopolysaccharide-induced nitric oxide release and proinflammatory cytokine expression in RAW264.7 cells.

In Vivo:

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin; orally; 5, 10, 20 mg/kg; 12 days) can inhibit trinitrobenzenesulfonic acid (TNBS)-induced ulcerative colitis (UC), reducing inflammatory response and alleviate colon muscle spasm.

Products are for research use only. Not for human use.

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