5, 15-Diacetyl-3-benzoyllathyrol


Catalog No. Size PriceQuantity
M26009-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

5,15-Diacetyl-3-benzoyllathyrol is one of the lathyrane diterpenoids, that has anti-cancer activity.

Product information

CAS Number: 218916-52-0

Molecular Weight: 522.63

Formula: C31H38O7

Chemical Name: (1R,5R,7S,11R,12R,13S,14S)-1,11-bis(acetyloxy)-3,6,6,14-tetramethyl-10-methylidene-2-oxotricyclo[10.3.0.0⁵,⁷]pentadec-3-en-13-yl benzoate

Smiles: CC1(C)[C@@H]2C=C(C)C(=O)[C@]3(C[C@H](C)[C@H](OC(=O)C4C=CC=CC=4)[C@@H]3[C@@H](OC(C)=O)C(=C)CC[C@H]12)OC(C)=O |c:4|

InChiKey: JPYYWXPAHJBKJX-JNRDNZLTSA-N

InChi: InChI=1S/C31H38O7/c1-17-13-14-23-24(30(23,6)7)15-18(2)28(34)31(38-21(5)33)16-19(3)27(25(31)26(17)36-20(4)32)37-29(35)22-11-9-8-10-12-22/h8-12,15,19,23-27H,1,13-14,16H2,2-7H3/b18-15-/t19-,23-,24+,25-,26-,27-,31+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

5,15-Diacetyl-3-benzoyllathyrol shows anticancer activity in vitro against lung cancer A549 cells and the IC50 values are 34.04±3.99 μM. Furthermore, 5,15-Diacetyl-3-benzoyllathyrol can induce apoptosis in A549 cells via the mitochondrial pathway including loss of mitochondrial potential and release of cytochrome c.

Products are for research use only. Not for human use.

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