GSK3395879


Catalog No. Size PriceQuantity
M26321-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

GSK3395879 is a selective and orally bioavailable transient receptor potential vanilloid-4 (TRPV4) antagonist with an IC50 of 1 nM for hTRPV4.

Product information

CAS Number: 2215852-91-6

Molecular Weight: 485.41

Formula: C20H15F4N3O5S

Chemical Name: 4-{[(3S,4R)-1-[2-cyano-4-(trifluoromethyl)benzenesulfonyl]-4-hydroxy-4-(hydroxymethyl)pyrrolidin-3-yl]oxy}-2-fluorobenzonitrile

Smiles: N#CC1=CC=C(C=C1F)O[C@H]1CN(C[C@@]1(O)CO)S(=O)(=O)C1=CC=C(C=C1C#N)C(F)(F)F

InChiKey: RAYCYIKGBWRQBC-RBUKOAKNSA-N

InChi: InChI=1S/C20H15F4N3O5S/c21-16-6-15(3-1-12(16)7-25)32-18-9-27(10-19(18,29)11-28)33(30,31)17-4-2-14(20(22,23)24)5-13(17)8-26/h1-6,18,28-29H,9-11H2/t18-,19+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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