Description
Pyrene azide 3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2252168-06-0
Molecular Weight: 444.53
Formula: C26H28N4O3
Chemical Name: N-{2-[2-(2-azidoethoxy)ethoxy]ethyl}-4-(pyren-1-yl)butanamide
Smiles: [N-]=[N+]=NCCOCCOCCNC(=O)CCCC1=CC=C2C=CC3C=CC=C4C=CC1=C2C=34
InChiKey: DXXWPTFNJXUJQL-UHFFFAOYSA-N
InChi: InChI=1S/C26H28N4O3/c27-30-29-14-16-33-18-17-32-15-13-28-24(31)6-2-3-19-7-8-22-10-9-20-4-1-5-21-11-12-23(19)26(22)25(20)21/h1,4-5,7-12H,2-3,6,13-18H2,(H,28,31)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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