Description
Boc-NH-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2062663-67-4
Molecular Weight: 375.46
Formula: C18H33NO7
Chemical Name: tert-butyl N-(3,6,9,12,15-pentaoxaoctadec-17-yn-1-yl)carbamate
Smiles: CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCC#C
InChiKey: KSXRJNCGVMUJQW-UHFFFAOYSA-N
InChi: InChI=1S/C18H33NO7/c1-5-7-21-9-11-23-13-15-25-16-14-24-12-10-22-8-6-19-17(20)26-18(2,3)4/h1H,6-16H2,2-4H3,(H,19,20)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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