Description
Propargyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2378150-09-3
Molecular Weight: 496.59
Formula: C23H44O11
Chemical Name: 3,6,9,12,15,18,21,24,27,30-decaoxatritriacont-32-yn-1-ol
Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChiKey: YMXJRYITKUOBEJ-UHFFFAOYSA-N
InChi: InChI=1S/C23H44O11/c1-2-4-25-6-8-27-10-12-29-14-16-31-18-20-33-22-23-34-21-19-32-17-15-30-13-11-28-9-7-26-5-3-24/h1,24H,3-23H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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