Description
Azido-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1818294-47-1
Molecular Weight: 545.45
Formula: C21H28F5N3O8
Chemical Name: 2,3,4,5,6-pentafluorophenyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate
Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCC(=O)OC1C(F)=C(F)C(F)=C(F)C=1F
InChiKey: YVHKCEARDWOLPA-UHFFFAOYSA-N
InChi: InChI=1S/C21H28F5N3O8/c22-16-17(23)19(25)21(20(26)18(16)24)37-15(30)1-3-31-5-7-33-9-11-35-13-14-36-12-10-34-8-6-32-4-2-28-29-27/h1-14H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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