m-PEG3-Sulfone-PEG4-propargyl


Catalog No. Size PriceQuantity
M26849-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

m-PEG3-Sulfone-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2055041-02-4

Molecular Weight: 426.52

Formula: C18H34O9S

Chemical Name: 1-{2-[2-(2-methoxyethoxy)ethoxy]ethanesulfonyl}-3,6,9,12-tetraoxapentadec-14-yne

Smiles: COCCOCCOCCS(=O)(=O)CCOCCOCCOCCOCC#C

InChiKey: RZOCFVBQMWCPJD-UHFFFAOYSA-N

InChi: InChI=1S/C18H34O9S/c1-3-4-22-7-8-24-9-10-25-12-14-27-16-18-28(19,20)17-15-26-13-11-23-6-5-21-2/h1H,4-18H2,2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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