Acid-C2-PEG4-C2-NHS ester


Catalog No. Size PriceQuantity
M26908-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Acid-C2-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1343476-41-4

Molecular Weight: 435.42

Formula: C18H29NO11

Chemical Name: 19-[(2,5-dioxopyrrolidin-1-yl)oxy]-19-oxo-4,7,10,13,16-pentaoxanonadecanoic acid

Smiles: OC(=O)CCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

InChiKey: QMACGMMKGUAJOY-UHFFFAOYSA-N

InChi: InChI=1S/C18H29NO11/c20-15-1-2-16(21)19(15)30-18(24)4-6-26-8-10-28-12-14-29-13-11-27-9-7-25-5-3-17(22)23/h1-14H2,(H,22,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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