Propargyl-PEG5-PFP ester


Catalog No. Size PriceQuantity
M26922-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Propargyl-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2148295-92-3

Molecular Weight: 470.38

Formula: C20H23F5O7

Chemical Name: 2,3,4,5,6-pentafluorophenyl 4,7,10,13,16-pentaoxanonadec-18-ynoate

Smiles: C#CCOCCOCCOCCOCCOCCC(=O)OC1C(F)=C(F)C(F)=C(F)C=1F

InChiKey: NWISPSNLWMLYFW-UHFFFAOYSA-N

InChi: InChI=1S/C20H23F5O7/c1-2-4-27-6-8-29-10-12-31-13-11-30-9-7-28-5-3-14(26)32-20-18(24)16(22)15(21)17(23)19(20)25/h1H,3-13H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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