Methyltetrazine-PEG4-amine


Catalog No. Size PriceQuantity
M26947-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Methyltetrazine-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1802908-05-9

Molecular Weight: 363.41

Formula: C17H25N5O4

Chemical Name: 3-[4-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)phenyl]-6-methyl-1,2,4,5-tetrazine

Smiles: CC1N=NC(=NN=1)C1C=CC(=CC=1)OCCOCCOCCOCCN

InChiKey: JOEAATMYJGXMGS-UHFFFAOYSA-N

InChi: InChI=1S/C17H25N5O4/c1-14-19-21-17(22-20-14)15-2-4-16(5-3-15)26-13-12-25-11-10-24-9-8-23-7-6-18/h2-5H,6-13,18H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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