THP-PEG10-THP


Catalog No. Size PriceQuantity
M26957-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

THP-PEG10-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 42749-29-1

Molecular Weight: 626.77

Formula: C30H58O13

Chemical Name: 2-{[29-(oxan-2-yloxy)-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-yl]oxy}oxane

Smiles: C(COCCOCCOCCOCCOC1CCCCO1)OCCOCCOCCOCCOCCOC1CCCCO1

InChiKey: ZLPQTQVPFMTVDO-UHFFFAOYSA-N

InChi: InChI=1S/C30H58O13/c1-3-7-40-29(5-1)42-27-25-38-23-21-36-19-17-34-15-13-32-11-9-31-10-12-33-14-16-35-18-20-37-22-24-39-26-28-43-30-6-2-4-8-41-30/h29-30H,1-28H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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