Amine-PEG3-Desthiobiotin


Catalog No. Size PriceQuantity
M26960-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Amine-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2237234-71-6

Molecular Weight: 388.50

Formula: C18H36N4O5

Chemical Name: N-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethyl)-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide

Smiles: C[C@@H]1NC(=O)N[C@@H]1CCCCCC(=O)NCCOCCOCCOCCN

InChiKey: RDKKYGNEWXGKMS-JKSUJKDBSA-N

InChi: InChI=1S/C18H36N4O5/c1-15-16(22-18(24)21-15)5-3-2-4-6-17(23)20-8-10-26-12-14-27-13-11-25-9-7-19/h15-16H,2-14,19H2,1H3,(H,20,23)(H2,21,22,24)/t15-,16+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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