Cbz-NH-PEG3-CH2COOH


Catalog No. Size PriceQuantity
M26975-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 462100-05-6

Molecular Weight: 341.36

Formula: C16H23NO7

Chemical Name: 2-{2-[2-(2-{[(benzyloxy)carbonyl]amino}ethoxy)ethoxy]ethoxy}acetic acid

Smiles: OC(=O)COCCOCCOCCNC(=O)OCC1C=CC=CC=1

InChiKey: DMBZCDPECWJRJR-UHFFFAOYSA-N

InChi: InChI=1S/C16H23NO7/c18-15(19)13-23-11-10-22-9-8-21-7-6-17-16(20)24-12-14-4-2-1-3-5-14/h1-5H,6-13H2,(H,17,20)(H,18,19)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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