HO-PEG10-CH2COOH


Catalog No. Size PriceQuantity
M26978-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

HO-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2250056-53-0

Molecular Weight: 516.58

Formula: C22H44O13

Chemical Name: 32-hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontanoic acid

Smiles: OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(O)=O

InChiKey: VEAWKHYVNPPKRE-UHFFFAOYSA-N

InChi: InChI=1S/C22H44O13/c23-1-2-26-3-4-27-5-6-28-7-8-29-9-10-30-11-12-31-13-14-32-15-16-33-17-18-34-19-20-35-21-22(24)25/h23H,1-21H2,(H,24,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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