Description
Bis-SS-C3-sulfo-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 98604-89-8
Molecular Weight: 592.60
Formula: C16H20N2O14S4
Chemical Name: 1-{[4-({4-[(2,5-dioxo-3-sulfopyrrolidin-1-yl)oxy]-4-oxobutyl}disulfanyl)butanoyl]oxy}-2,5-dioxopyrrolidine-3-sulfonic acid
Smiles: OS(=O)(=O)C1CC(=O)N(OC(=O)CCCSSCCCC(=O)ON2C(=O)C(CC2=O)S(O)(=O)=O)C1=O
InChiKey: RIUSVHPDQDXRGU-UHFFFAOYSA-N
InChi: InChI=1S/C16H20N2O14S4/c19-11-7-9(35(25,26)27)15(23)17(11)31-13(21)3-1-5-33-34-6-2-4-14(22)32-18-12(20)8-10(16(18)24)36(28,29)30/h9-10H,1-8H2,(H,25,26,27)(H,28,29,30)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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