PPC-NHS ester


Catalog No. Size PriceQuantity
M27012-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 107348-47-0

Molecular Weight: 326.39

Formula: C13H14N2O4S2

Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate

Smiles: CC(CC(=O)ON1C(=O)CCC1=O)SSC1=CC=CC=N1

InChiKey: VQZYZXLBKBUOHE-UHFFFAOYSA-N

InChi: InChI=1S/C13H14N2O4S2/c1-9(20-21-10-4-2-3-7-14-10)8-13(18)19-15-11(16)5-6-12(15)17/h2-4,7,9H,5-6,8H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Products are for research use only. Not for human use.

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