Description
Butyl isobutyl phthalate is isolated from the rhizoid of Laminaria japonica. Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor with an IC50 value of 38 μM. Butyl isobutyl phthalate shows a hypoglycemic effect and has the potential for diabetes treatment.
Product information
CAS Number: 17851-53-5
Molecular Weight: 278.34
Formula: C16H22O4
Chemical Name: 1-butyl 2-(2-methylpropyl) benzene-1,2-dicarboxylate
Smiles: CCCCOC(=O)C1=CC=CC=C1C(=O)OCC(C)C
InChiKey: UVIVWIFUPKGWGF-UHFFFAOYSA-N
InChi: InChI=1S/C16H22O4/c1-4-5-10-19-15(17)13-8-6-7-9-14(13)16(18)20-11-12(2)3/h6-9,12H,4-5,10-11H2,1-3H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : ≥ 250 mg/mL (898.18 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Butyl isobutyl phthalate exhibits significant, concentration-dependent inhibitory activity against α-glucosidase with an IC50 value of 38 μM.
In Vivo:
Butyl isobutyl phthalate (intragastric administration; 25, 50 or 100 mg/kg; 3 days) results in a more significant reduction in the blood glucose level, with the concentration of blood glucose being 11.50, 8.60 and 6.50 mM, respectively.
Products are for research use only. Not for human use.
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