Gefitinib impurity 5


Catalog No. Size PriceQuantity
M27468-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Gefitinib impurity 5 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity.

Product information

CAS Number: 199327-61-2

Molecular Weight: 319.36

Formula: C16H21N3O4

Chemical Name: 7-methoxy-6-[3-(morpholin-4-yl)propoxy]-3,4-dihydroquinazolin-4-one

Smiles: COC1=CC2N=CNC(=O)C=2C=C1OCCCN1CCOCC1

InChiKey: WFUBWLXSYCFZEH-UHFFFAOYSA-N

InChi: InChI=1S/C16H21N3O4/c1-21-14-10-13-12(16(20)18-11-17-13)9-15(14)23-6-2-3-19-4-7-22-8-5-19/h9-11H,2-8H2,1H3,(H,17,18,20)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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