Description
KDM4-IN-2 (Compound 19a) is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7 nM for KDM4A and KDM5B, respectively.
Product information
CAS Number: 2369607-62-3
Molecular Weight: 426.51
Formula: C25H26N6O
Chemical Name: 8-[4-(2-{2,3-dihydrospiro[indene-1,4'-piperidin]-1'-yl}ethyl)-1H-pyrazol-1-yl]-3H,4H-pyrido[3,4-d]pyrimidin-4-one
Smiles: O=C1NC=NC2=C(N=CC=C21)N1C=C(CCN2CCC3(CCC4=CC=CC=C34)CC2)C=N1
InChiKey: AVFIHINZEZRGBL-UHFFFAOYSA-N
InChi: InChI=1S/C25H26N6O/c32-24-20-6-11-26-23(22(20)27-17-28-24)31-16-18(15-29-31)7-12-30-13-9-25(10-14-30)8-5-19-3-1-2-4-21(19)25/h1-4,6,11,15-17H,5,7-10,12-14H2,(H,27,28,32)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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